Agents West and Gordon are guarding a museum containing the famous Herzberg jewels but someone still manages to steal the gems. Afterward, a famous painting of a Western scene is removed from the museum by its wealthy rancher-owner. Gordon becomes suspicious and notifies West who discovers that the rancher is partners with Miguelito Loveless, the evil inventor-doctor. His latest invention is a machine that moves real people in and out of paintings. Miguelito's plan is to transpose murderers into famous paintings, distribute the paintings to the rulers of the world, and have them all killed!